Par Véronique Gouverneur
TITRE: Late Stage Fluorination with Metal Alkali Fluoride
Exceptionnellement à 10:00
Hôte: Prof. Hélène Lebel
LIEN ZOOM:
https://umontreal.zoom.us/j/95023293134?pwd=dDNhUThWdktCQ1NtY2p4Ymp4V0xXUT09
ID de réunion : 950 2329 3134
Code secret : 240221
RÉSUMÉ: The invention of chemical reactions to create fluorine-containing molecules is an important aspect of modern medicine. Positron Emission Tomography (PET) with short-lived 18F-radiotracers is an imaging modality that can diagnose diseases, and monitor how patients respond to therapy. Moreover, the stable isotope 19F is commonly used in drug discovery to identify lead molecules and improve their properties.Over the years, we have invented numerous reactions to advance fluorine-based medicine, a rewarding process that has enhanced our fundamental understanding of fluorine chemistry, more specifically metal alkali fluoride reactivity. This lecture will focus on the challenges of working with metal alkali fluoride and some of the novel solutions developed recently in our laboratory.
